Oct 25, 2023 · The present study focuses on the development and validation of an HPLC-DAD methodology for the detection of a potent chemotherapeutic agent, Maytansinoid Ravtansine (DM4), …

DM4 (hydrate): A derivative of maytansine. Synonym: Maytansinoid DM 4. Purity: ≥95%.

Things just got a little more despicable. DM4 hits theaters July 3. --TikTok: https://www.tiktok.com/@minionsFacebook: https://uni.pictures/MinionsFBX: http...

Dec 16, 2025 · DM4 is a thiol-containing compound that undergoes methylation within cells through the activity of methyltransferases, forming S-Me-DM4. This metabolite demonstrates notable cytotoxicity.

A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to a toxic substance called maytansinoid DM4.

DM4, a chemical derivative of maytansine, is a potent and selective cytotoxic agent that inhibit cell division. Buy Microtubule inhibitor DM4 (Maytansinoid DM4) from AbMole BioScience.

Jul 7, 2024 · DM4, which began a staggered overseas release pattern a few weeks back, now counts $229.5M globally with several key majors still to come including France, Germany, China, UK, …

DM4 (ravtansine) is a semisynthetic analogue of maytansine with a C3 ester side chain bearing a dimethyl hindered thiol substituent. It binds to tubulin and inhibits the assembly of microtubules.

Enhance your life-science and clinical research with the DM4 B and DM6 B upright microscopes. Optimized for imaging tissue and plant specimens, as well as pathology, these microscopes are …

DM4-d6 is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate. - Mechanism of Action & Protocol.