Fluorescence nanoscopy has transformed our ability to visualize and discover biological structures. In recent years, ultraprecise single-molecule localization techniques such as MINFLUX and RASTMIN ...

An international collaboration of researchers developed two new complementary approaches for versatile but precise light intensity measurements in fluorescence imaging systems. Accurate measurements ...

It is the computational processing of images that reveals the finest details of a sample placed under all kinds of different light microscopes. Even though this processing has come a long way, there ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...

A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers have succeeded in developing a microscope ...

QIScope: When imaging low protein levels in live cells on the high-sensitivity QIScope, bioluminescence (blue) significantly outperforms fluorescence (green). (Courtesy: Ruyu Ma - Helmholtz Munich) A ...