In clinical routine pathology today, detection of protein in intact formalin-fixed, paraffin-embedded tissue is limited to immunohistochemistry, which is semi-quantitative. This study presents a new ...

These inconsistencies may be explained by usage of different decalcifying agents. Strong acids such as hydrochloric and nitric acid are traditionally widely used for their rapid decalcifying ...

Personalized medicine depends on tools, such as immunohistochemistry (IHC), that identify precise targets in a patient’s disease. Immunohistochemistry (IHC) staining is integral in developing ...

Immunohistochemistry uses antibodies to test tissue samples for specific types of antigens. It can often provide very specific results regarding cancer types or other diseases, helping doctors decide ...

The first study using IHC was published in the 1940s when antigens of bacterial species Streptococcus pneumonia were discovered in the tissues. Since then, a wealth of developments and several ...